Computerized cognitive therapy improved her cognitive function, from a Korean version of the Mini-Mental State Examination score of 23 on the first admission to 30 on final discharge. On the second admission, her FIM motor score was 42, but after continuous multidisciplinary rehabilitation, it improved to 76. However, 4 months after discharge, the disease relapsed with symptoms of motor weakness in all extremities, and steroid treatment was initiated. After 5 weeks of rehabilitation involving physical therapy, occupational therapy, and balance training, her FIM motor score improved to 60. Initially, her Functional Independence Measure (FIM) motor score was 26, allowing her to stand independently for only a few seconds. After pharmacologic therapy, the patient was transferred to the rehabilitation department. She was diagnosed with MOGAD and received intravenous steroid pulse therapy. The patient's serum tested positive for anti-MOG antibodies. She visited the neurology department, and early brain and spine magnetic resonance imaging showed multifocal high intensity in the subcortical and periventricular white matter and the cervical cord. A 58-year-old woman developed weakness in all extremities, dysarthria, and dysphagia. Here, we present a case of MOGAD that showed significant recovery after rehabilitation. MOGAD has recently been recognized as an autoimmune disease therefore, little is known about its rehabilitation. Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is an inflammatory central nervous system disease that is driven by antibodies of the immunoglobulin G1 class.
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